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Pepsinogen I Detection Kit (Latex-Enhanced Immunoturbidimetric Method)

Pepsinogen is a precursor of protease secreted by gastric mucosa, which can be divided into pepsinogen I (PG I) and pepsinogen II (PG II). Serum pepsinogen can accurately display the symptoms and functions of gastric mucosa.
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Description

Pepsinogen is a precursor of protease secreted by gastric mucosa, which can be divided into pepsinogen I (PG I) and pepsinogen II (PG II). Serum pepsinogen can accurately display the symptoms and functions of gastric mucosa. The detection of PG, especially the ratio of PG I/PG II and the level of PG I, is very valuable for the diagnosis of intestinal metaplasia in chronic atrophic gastritis.


Clinical significance 

✔ Dynamic monitoring of individual gastric mucosal function 

✔ Screening for Helicobacter pylori (HP) infection in gastric ulcer atrophic gastritis

✔ Evaluation of HP therapeutic efficacy

✔ The determination index of peptic ulcer recurrence cure 


Reagent performance 

Sample type

Serum

Linear range

2.5-160 ng/mL

Precision within batch

≤ 7%

Precision between batch

≤ 9%

Reference range

PGI ≥ 70.00 ng/mL

And PGI/PGII ≥ 3.0


Application department 

Physical Examination Center, Digestive Department, Laboratory Department 


Product specification 

Packing specification

Bottle number x capacity

32 mL

R1: 1x27 mL + R2: 1x5 mL (optional calibration product, quality control product)

64 mL

R1: 1x54 mL + R2: 1x10 mL (optional calibration product, quality control product)

128 mL

R1: 2x54 mL + R2: 1x20 mL (optional calibration product, quality control product)

256 mL

R1: 3x72 mL + R2: 1x40 mL (optional calibration product, quality control product)

5x1 mL(Calibration product)

Calibration level 1: 1x1mL (liquid) 

Calibration level 2:1 x 1 mL (liquid)

 Calibration level 3: 1x1mL (liquid)

 Calibration level 4:1 x 1 mL (liquid)

 Calibration level 5: 1x1mL (liquid)

2x1 mL(Quality control product)

Quality control level 1: 1x1mL (liquid) 

Quality control level 2: 1x1mL (liquid)


Supporting instruments 

Hitachi, Abbott, Beckman, Dirui, AU400 and other Automatic Biochemical Analyzer 


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